Studies on the Eudocrine (J lands 837 



localised to any one place. The pars intermedia shows numerous vesicles 

 some of them containing hyaline masses. The pars nervosa is open in 

 texture, and shows here and there the usual small droplets of hyaline 

 substance: these do not appear increased in amount. 



Summary of Observations on the Dog. 



The effects of thyroidectomy — which was only partial, since it was 

 desired to leave the parathyroids in situ — have been to cause changes in 

 the pituitary consisting in the accumulation of colloid between the cells 

 of the pars anterior, such as has been described by previous investigators, 

 and an especial development of oxyphil cells, as well as the appearance 

 of many swollen — possibly degenerating — cells, some of which are seen to 

 surround clear vesicles. In the case described there was a cyst-like 

 expansion of the intraglandular cleft in the pars anterior, but whether 

 the result of the thyroidectomy or not, cannot be stated. The pars inter- 

 media was thickened, and contained many vesicles, surrounded by cells, 

 and occupied by masses of hyaline substance. These vesicles extend here 

 and there into the pars nervosa. 



The chief effect of partial parathyroidectomy was to produce an 

 oedematous condition of all parts of the pituitary. Oxyphil cells appeared 

 more abundantly than usual in the pars anterior, but there were no such 

 striking changes in the gland as are caused by thyroidectomy. 



BIBLIOGRAPHr. 



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