98 .POULTRY DISEASES 



pullorum was isolated from the heart, blood, liver, 

 spleen and kidneys, and in every case the coc- 

 cidian ulcers, described above, were observed. 



These chicks began dying in numbers at about 

 ten days of age, very few had died before that 

 time, and from this period to the end of the third 

 week the great loss occurred. After this time but 

 few died, but those having the disease in light 

 form were stunted and did not make satisfactory 

 growth. With this data now before me, I now 

 began on another line of treatment. 



During the past ten years I have used, to a 

 greater or less extent, dilutions of mercuric chlor- 

 ide (corrosive sublimate) as an intestinal anti 

 septic in chickens. This was used, in this outbreak, 

 in a solution of 1 : 10,000, with sulphocarbolates 

 of zinc, sodium and calcium. The latter had not 

 given the satisfactory results when used alone 

 that it had in treatment of diarrhea in colts and 

 calves. 



Jones (Cornell) has shown that a solution of 

 1 : 1,000 (one-tenth of one per cent) bichloride of 

 mercury, will kill the B. pullorum in thirty sec- 

 onds; a one per cent carbolic acid solution re- 

 quires five minutes in which to kill this germ ; one 

 per cent creolin requires five minutes; three and 

 one-third per cent lactic acid kills it in five min- 

 utes, and ^YQ per cent carbolic acid kills it in 

 thirty seconds. Mercuric chloride is therefore 

 fifty times as effective against this germ as is 

 carbolic acid. 



Instructions were given for the incubators (con- 

 taining also the nursery trays) to be tightly closed 

 and fumigated with formaldehyde gas, as recom- 

 mended under chicken cholera, before filling with 

 eggs. 



