20 SMAM.-l'OX I\ SIIKF.r. 



this disease to small-pox in the human subject, and the 

 identity of the two was further proved by the fatality 

 of the affection in the febrile and third stages ; upwards 

 of twenty sheep having already died, and others being 

 in that state which precluded all hope of ultimate re- 

 covery. 



The treatment recommended in the fast stage con- 

 sisted of a dose of laxative medicine at the onset, fol- 

 lowed by the daily exhibition of mild diffusible stimu- 

 lants, in conjunction with febrifuges ; such as the spirit 

 of nitric ether, acetate of annnonia, and very small 

 quantities of the antimonial compoimds. After the 

 acuteness of the attack had passed off, vegetable and 

 mineral tonics conjoined were administered, as the 

 compound tinctures of bark and gentian, and the sul- 

 phate of iron. 



When there \vere symptoms of approaching ulcera- 

 tion of the cutis, a very dilute solution of the chloride 

 of zinc was applied ; and the same was directed to be 

 used w^hen the ulcerative stage was established. Care- 

 ful nursing, and generous and varied diet, were espe- 

 cially enjoined. 



As prophylactic measures, isolation of the apparently 

 healthy sheep was strictly enforced, with daily inspec- 

 tion, and instant removal of any in which the slightest 

 indication of the affection manifested itself. The exhi- 

 bition of aperients occasionally, the feeding of the ani- 

 mals on grass land where they could have access to 

 water, and the placing of rock salt in their troughs, 

 were also recommended. 



Mr. Statham, at my request, kindly forwarded two 

 sheep to the Royal Veterinary College, one being in the 

 first, and the other in the third stage of the disease. That 



