INOCULATION WITH OVINE VIUUS. 29 



was enabled this morning to procure some lympli from 

 tlie matured vesicles : this was reserved by him for 

 future experiments. 



Sept. 23. — A few of the scabs on the prepuce are 

 of a still darker colour, and are surrounded by a whitish 

 raised border, from which a small quantity of fluid re- 

 sembling pus can be pressed. 



Sept, 24. — The animal may be reported as ap- 

 proaching convalescence. The majority of the crusts 

 have become detached, and the exposed surfaces pre- 

 sent a healthy appearance. 



The attack in this instance was the mildest we have 

 yet seen ; but the result has been perfectly satisfactory, 

 and the deductions to be drawn fi*om it are obvious, no 

 interference whatever having been given to the progi-ess 

 of the disease throughout its various stages. 



Experiments 2 and 3. 



Sept. 13. — An Irish sheep, in perfect health, was this 

 day inoculated from one of Mr. Statham's sheep ; for 

 this purpose we used some cuticle the cells of which 

 were charged with lymph, and which had been removed 

 on the 7th inst. from the surface of the nodules in their 

 second stage. A portion of it was inserted inside the 

 fore arm and the ear, by puncturing the skin with a 

 lancet, and separating it from the subcutaneous struc- 

 ture ; the cuticle containing the virus being placed hi 

 the wound. 



Another sheep was similarly inoculated ; but in ad- 

 dition to the portions of epidermis, some ;;w5, procured 

 from an animal in which ulceration had taken place as 

 a result of the malady, was also introduced underneath 

 the true skin. 



