INOCULATION. 107 



quoted, inoculated six laiubs, two on the second day 

 after their birtli, two on the third, and the others on 

 the fourth : five of the number died in the eruptive, 

 and the other in the second stage of the disease. Si- 

 milar experiments have been repeated by other persons, 

 and always with analogous results. With the excejD- 

 tion of very young animals, sheep of any age may be 

 ovinated; but it is necessary to select the lymph 

 from the m'lldcst cases, and to choose, if possible, 

 temperate weather for the performance of the opera- 

 tion. In the opinion of Captain Carr, " the most 

 favourable season for yearly inoculation is late in the 

 spring, or early in the autumn*." 



Many other precautions are needed to secure success ; 

 but we refrain for the present from entering fully into 

 these particulars, being desirous of first recording some 

 of our early experiments of ovination. 



On October 22, a healthy sheep, of the Leicester 

 breed, was inoculated ; three small punctures were 

 made, one inside each thigh, and the other on the 

 postero-inferior part of the abdomen ; points charged 

 with lymph procured the preceding day, were inserted 

 into two of the punctures, and a portion of cuticle, 

 impregnated ^^'ith the ichor into the third. 



Oct. 25. — The incision into which the scab was 

 placed has taken on the suppurative action : no change 

 is observed in the other inoculated places. 



Oct. 2G. — A small ulcer, surrounded by a slight 

 areola, exists where the cuticle was used. The otlier 

 incisions are marked by eccentric spots of a deep red 

 colour. 



* Sheep-pox, p. II. 



