LNOCULATION. 109 



but no fluid can be detected beneath it {plate 5). 

 Vesicles are formed on the papulae, from which we 

 succeeded in charging a few points. 



Nov. 6. — The patient's health is much improved, but 

 the punctures are beginning to ulcerate. 



Nov. 8. — Eighteenth day. Dark-coloured scabs ad- 

 here to the surface of the ulcers; these are sur- 

 rounded by purulent formations distending the epi- 

 dermis, and imparting to it a yellow aspect {2)]ate 5). 



Nov. 12. — The ulcerative process has not pene- 

 trated the dermis ; the sores look healthy, and require 

 only time to heal them. The animal is convalescent. 



On the same day that the subject of the preceding 

 experiment was operated on, we ovinated another 

 sheep, using fresh dried lymph for the purpose, and 

 making the punctures on the brisket and abdomen. 



Oct. 25. — One incision on the abdomen presents an 

 appearance similar to a flea-bite, but with a greater 

 thickening of the integument. 



Oct. 26. — Two more of the punctures are in- 

 flamed. 



Oct. 29. — The red spots have extended daily up to 

 this time : they now shew an alteration in colour, and 

 a falling-in of the centre. As in the former case, these 

 changes are associated with symptoms of fever, and 

 with a rose-coloured eruption. 



Oct. 31. — The constitutional symptoms are aug- 

 mented : the patient is very dispirited, and stands 

 moping about ; the visible mucous membranes are in- 

 jected; the skin is hot, the pulse rapid, and the 

 breathing increased. Papulae can be detected on those 

 parts of the body that are generally the first affected. 



Nor. 2. — Fifth day of eruption and twelfth of oviuiX- 



