LYMPH OF TNOCUr.ATKl) VKSICLKS. 110 



inoculated places, became iiKlurated. Yet it was not 

 till the eleventh day of the eruption and sixteenth of the 

 inoculation y that amj hjmph could he procured from either 

 the eruptive or the inoculated vesicles" 



It is the opinion of Hurtrel D'Arboval, that the ex- 

 udations of the inoculated vesicles, although limpid, are 

 not equally efficacious in communicating the disease as 

 those of the eruptive vesicles : extended experience is 

 needed to test the correctness of this declaration, as 

 both Mr. Ceely and ourselves have succeeded in inocu- 

 lating sheep with the contents of these vesicles, and 

 have not observed the difference spoken of. 



The inoculated vesicles are in general much larger 

 than those formed on the papulae, and the fluid they 

 contain is less viscid ; but if it can be depended on, an 

 advantage will result, for very frequently the others 

 will not yield any lymph, the whole having been im- 

 bibed by the cells of the cuticle. Much time and ])a- 

 tience are required in procuring a supply of ichor for 

 inoculation, even from fully developed vesicles ; and an 

 hour will often be spent in well charging a dozen points. 

 Mr. Ceely in one of his communications says, " I was 

 occupied two hours in charging twelve tubes, and 

 twenty points and lancets : the latter were twice co- 

 vered. I found that by waiting a few minutes after 

 taking up the fluid from the surface of the vesicles, a 

 further exudation equally lim])id took place. I am not 

 disposed from analogy to expect that the later dis- 

 charge even of an eruptive vesicle, is equal to the earlier. 

 In the vaccine disease only the first exudations are of 

 any value ; still I do not think that analogy alone will 

 suffice to determine this point." 



As we were desirous of testing the power of the 



