12R SMALL-l'OX IN SIIKKP. 



Dec. G. — The roseola has disappeared ; a few stigmata 

 remain, but no papulte can be detected. 



Dec. 8.— The constitutional disturbance has passed 

 off'; resides are forming on the itioculaied j)laces : with 

 this exception, the skin has regained its normal con- 

 dition. 



Dec. 14. — The suppurative action has commenced, 

 and pus is mingled with the contents of the vesicles, 

 virtually changing them into pustules. 



Dec. 18.— The pustules are drying up; superficial 

 ulceration exists, but it has no tendency to spread. 

 — During the succeeding week the scabs were thrown 

 off, and the sores had nearly healed. 



This case is satisfactory, and clearly indicates that 

 the lymph was rendered less virulent by the removes to 

 which it had been subjected. Nevertheless, many si- 

 milar experiments must be instituted, before positive 

 assertions can be made on so important a subject. We 

 *do not hesitate, however, to express our belief, that the 

 most likely way to make the lymph milder, and better 

 suited for ovination, is, to pass it through the systems 

 of several healthy sheep. Ten removes are probably 

 required for this purpose. 



As inoculation is frequently adopted to limit the ra. 

 vages of the small-pox, when the natural disease has 

 shewn itself in a flock, (the unaffected animals being 

 subjected to the operation, and allowed to remain with 

 the others,) we determined on exposing an animal to the 

 contagion, and ovinating it during the time. The ex- 

 periment was unattended with any aggi'avation or ir- 

 regularity of either the local or general symptoms, as 

 the following details will shew. 



