GANGRENOUS TUMOURS. l^iS 



tietli days of ovination ; and when it tends to sphacelus, 

 we find that at the commencement it is liard, and sur- 

 romided by an areola, and by ccdematous swelhng. It 

 is at first red and very painful, but soon becomes of a 

 bluish colour. Fresh parts are quickly involved in the 

 morljid action, and ultimately sloughing takes place. 

 When the tumour has less tendency to end in gan- 

 grene, the swelling and hardness are not so marked, 

 and the skin has a yellowish hue*." These local 

 effects are invariably accompanied with great febrile 

 excitation, and most of the symptoms of which we have 

 previously made mention are ushered in with rapidity ; 

 diarrhcea generally being the immediate cause of death. 

 D'Arboval however adds, that " he has not once noticed 

 the formation of these gangrenous tumours in nearly 

 twelve hundred inoculations of sheep, a thousand of 

 which were operated on by superficial punctures made 

 on the postcro-inferior part of the abdomen ; and that 

 in order to become acquainted with their history, he 

 has perused the writings of Calignon, La Peyrouse, 

 Vignerie, Voisin, Dupuy, and Girard, from the two 

 latter of which he has derived the most informationf ." 



* Article Clavelization. 

 t Ibid. 



