142 SMALL-POX L\ SHKKP. 



Ciliated disease, he maintains " that one preventive is 

 as beneficial as the other, and that every person must 

 admit the great superiority of vaccination, as it does 

 not produce a contagious malady." He also says 

 that, " at the time he was requested by the Sove- 

 reign of Lucca to carry out vaccination in her states, 

 he, assisted by Joubert, surgeon to the royal house- 

 hold, vaccinated her JNIajesty's Merino sheep with the 

 most satisfactory result. And that M. Spada, of Ma- 

 cerata, who keeps a considerable number of Merino 

 sheep, having learnt how to perform the operation, 

 continued the practice on his estates, and likewise ex- 

 tended it to the children of his tenants ; so that the 

 small-pox, of late years, has not even been heard of 

 either among men or sheep in that district." And again, 

 that '' M. Dandolo, purveyor general of Dalmatia, has 

 his sheep vaccinated in Varese, a province in Lombardy, 

 as a precautionary measure, for as yet variola ovina is 

 unknown there : the operation is usually performed by 

 his brother-in-law. Dr. Grossi, who has employed the 

 vaccine lymph regenerated in the sheep with perfect 

 success for vaccinating children." 



When describing the cow-pox as developed in the 

 sheep, Sacco thus writes : — *' the phenomenon which 

 accompanies the inoculation of sheep with vaccine 

 lymph is deserving of particular notice ; the eruption of 

 the pustules [?] takes place regularly, but they are 

 mostly resolved before coming to maturity ; the cutis 

 detaching itself in small scales from their surfaces as 

 from the pustules [?] of ovine variola. It is very seldom 

 that true vesicles are produced which are succeeded by 

 the formation of scabs." The same thing he has ob- 

 served in the pig ; and he asks " whether the pecu- 



