OVINATION AITKR VACCINA'i'IOX. 145 



Twelfth day. — Vesicles are forming on the inflamed 

 incisions. The papiilas are stationary, from which we 

 infer that they will be removed without passing through 

 their several sttiges. 



Fourteenth day. — The inoculated vesicles are well 

 developed, and we are able to charge several points ; 

 the fluid is limpid, but not very viscid. Branny scales 

 are falling from the surfaces of the imperfectly matured 

 papulag. 



Sixteenth day. — Patches of whitened cuticle par- 

 tially adhere to the sites of the inoculation ; a small 

 quantity of purulent matter encircles them; and the 

 cutis is beginning to ulcerate. 



Twentieth day. — The ulcers are superficial, and have 

 a healthy appearance. 



Sheep D. 



Fourth day of ovination. — One incision on the side 

 of the sternum and another on the postero-inferior part 

 of the abdomen have ta^ken. 



Sixth day. — The inflammation excited by the virus 

 has spread around each incision, and attained the size 

 of half-a-crown. 



Seventh day. — No further increase of the inflamma- 

 tion has taken place, but an eruption has broken out, 

 being chiefly confined to the upper and inner part of 

 the limbs. A febrile state of the system also exists, 

 and the animal refuses food. 



Eighth day. — With the exception of the ovinatcd 

 places being umbilicated, there is very little change in 

 either the local or constitutional symptoms. 



Tenth day. — Tlie patient's health is improved, the 



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