152 SMALI- rdX IN SHKKP. 



subject or the cow, and thus destroy the virulence of 

 the virus." And again, lie says, " as it is found that 

 tlie vaccination of sheep gives immunity, so likewise 

 does the ovulation of man render him secure against 

 the small-pox." 



On a matter of so much importance as tliis, more 

 especially as the experiments adopted in this country 

 have been unattended with success, we shall not hesi- 

 tate to subjoin copious extracts from the writings of 

 the same authority. " The first time," says he, " that 

 I saw the small-pox in sheep, was in 1804, when pass- 

 ing through Capua, in the kingdom of Naples, my at- 

 tention was directed to seven sheep which a man was 

 driving into a butcher's shop, and which had such a 

 dejected appearance, that I stopped to examine them. 

 Having satisfied myself that the animals were affected 

 with variola, I carefully collected some of the virus 

 from the finest pustules [?] with the intention of ex- 

 perimenting with it as early as possible. On Christmas 

 day of the same year, on my way home, I called on 

 Dr. Legni, of Cattolica, and informed him of my wish : 

 he procured six children, and these we inoculated with 

 the ichor, which was still fluid. For the sake of com- 

 parison, two other children were vaccinated with 

 genuine lymph. A month afterwards Dr. Legni in- 

 formed me that all the cases had gone on in the ordinary 

 way, and that he had not observed any marked dif- 

 ferences between the effects produced by the vaccine 

 and those of the ovine inoculation. He also stated 

 that he had since used the ovine lymph on nearly 300 

 children with the most complete success." 



" I subsequently determined to inoculate two chil- 



