(JVINATION OK OXKN. 155 



all the above subjects were shortly afterwards vacci- 

 nated with current vaccine lymph, which in each case 

 exhibited the normal effects. I may as well add, also, 

 that the same kind of ovine virus which did not succeed 

 on children, took promptly on sheep." 



Thus it is evident that the difficidty of conveying the 

 small-pox of sheep to man is greater than Sacco would 

 lead us to suppose ; even if we admit the susceptibility 

 of the human subject to be affected by the disease. And 

 with regard to the inoculation of the cow with ovine 

 virus, a practice which is likewise advocated by the same 

 author as a certain method to purify the lymph and 

 render it mild, we have to observe that our efforts to 

 accomplish this have also been unsuccessful. 



On Oct. 19, a heifer was ovinated with primary 

 lymph of good quality, wliich was inserted while yet 

 fluid into four punctures on the labia, and also smeared 

 over several groups of scratches on the teats ; in ad- 

 dition to this some crusts were reduced to powder, 

 and placed beneath the cuticle on the inside of the 

 ears. No specific effects followed. The experiment, 

 with slight modifications, was thrice repeated on the 

 same animal, and each time failed. 



On Nov. 5, another heifer was inoculated in three 

 punctures on each side of the labia, and in two 

 others a little below it : the lymph used was the second 

 remove fi'om the sheep. The incisions inflamed rather 

 more than ordinarily ; but all the effects had passed off* 

 by the seventh day. 



Nov. 16. — This animal was re-ovinated with fresh 

 lymph taken from a confluent case of sheep-pox, wliich 

 also proved ineffective. The experiment was again 

 repeated without success. 



