192 A MANUAL OF BACTERIOLOGY 



the microbes themselves as foreign bodies, destroy 

 them. When the cells are suddenly attacked by a 

 strong dose of the poison of this virus they are so 

 paralysed that the microbes can continue to carry 

 on their poison-manufacturing process without let 

 or hindrance ; but when the cells are gradually 

 though rapidly, accustomed to the presence of the 

 poison by the exhibition of constantly-increasing 

 doses, they can carry on their scavenging work even 

 in its presence, and the microbes are destroyed, 

 possibly even before they can exert their full poison- 

 manufacturing powers. Some such explanation as 

 this would account for the interference with the 

 course of the disease even after the patient has been 

 bitten. The microbe is localised, it takes some 

 time to form its poisonous products, and whilst this 

 is going on the whole of the nervous and other 

 tissues are being gradually acclimatised by the 

 direct application of small quantities of the poison 

 artificially introduced.' 1 



In concluding our remarks concerning rabies, it 

 may be stated that the rabid marrows can be pre- 

 served for several months in pure and neutral 

 glycerine. Hence the use of this fluid for preserv- 

 ing the marrows (for inoculation against rabies) 

 during their transit from France to foreign countries. 



For further information the reader is referred to 

 the undermentioned books and papers on the 

 subject. 2 



1 Woodhead's Bacteria and their Products, p. 327. 



2 Pasteur in Comptes Rendus, 1881-86; Dolan's Hydrophobia : 

 M. Pasteur and his Methods ; Gamaleia in Annales de VInstitut 



