INFECTIOUS DISEASES AND MICROBES, ETC. 207 



the interstitial tissue of the nerves. B. leprce is 

 sometimes motile and produces spores. It grows 

 on blood serum and alkaline infusions of meat- 

 extract ; and Damsch 1 has produced the disease in 

 cats by inoculating them with leprous tissues. The 

 microbe is absent in the blood of lepers ; therefore 

 it probably spreads by the lymphatic vessels. 



Hansen's discovery 2 of B. leprce lias since been con- 

 firmed by Neisser, 3 Cornil, 4 Babes, 5 Hillis, 6 Stevens, 7 

 Thin, 8 Rake, 9 Kobner, 10 Bordoni-Uffreduzzi, 11 and 

 Gianturso ; 12 and during the present Leprosy Com- 

 mission in India, Drs. Rake, Buckmaster, Thomson, 

 and Kanthack have also succeeded in rearing B. 

 leprce 13 on blood serum ; but growths of this microbe 

 are difficult to obtain. Bordoni-Uffreduzzi obtained 

 ' growths from the marrow of a bone in which there 

 were a number of free leprosy bacilli ; these appeared 

 on serum (to which a quantity of glycerine had been 

 added) that was maintained at a temperature of 37 

 C. These he described as delicate, thin, slightly 



I Virchow's Archiv, vol. xcii. 



9 Ibid. vol. Ixxix. 3 Ibid. vol. Ixxxiv. 



4 Union Medicate, 1881. 



5 Archives der Physiologic, 1883. 



Transactions of Pathological Society, 1883. 



7 British Medical Journal, 1885. 



8 Med.-Chir. Transactions, vol. Ixix. 



9 Transactions of PathoL Soc., 1887. 



10 Virchow's Archiv, vol. Ixxx. 



II Zeitschrift fur Hygiene, vol. iii. p. 178. 



12 Centralblatt fur Bakteriologie und Parasitenkunde, vol. ii. 

 p. 701. 



13 Concerning the differences between the leprosy and tubercle 

 bacilli, 'see Slater's paper in Quart. Journ. Micros. Science, 1891, 



