234 A MANUAL OF BACTERIOLOGY 



has only diminished about 60 per cent., so that 

 there still remain certain factors that favour the 

 spread of cholera, and every now and again such a 

 spread or outbreak may take place with extreme 

 rapidity, and may involve a very wide area. 

 Cleanliness, however, both general and personal, 

 may be said to be the most important factor in the 

 prophylaxis of cholera/ 



It should be borne in mind that in cases of 

 cholera, isolation and disinfection are absolutely 

 necessary to prevent the disease spreading. 1 For 

 further information on the subject of cholera and 

 its microbe, the reader is referred to the under- 

 mentioned works. 2 



GLANDERS. 



This contagious infective disease is caused by the 

 Bacillus mallei (Fig. 33, 12), which has been found 

 in the lungs, liver, spleen, and nasal membranes of 

 horses and sheep dead or dying from glanders. 



The same microbe has been found in human 

 glanders or farcy ; and the death of Dr. Hoffmann, 

 of Vienna, in 1889 is a standing proof of the patho- 

 genic nature of this microbe, and its being the cause 

 of the disease known as glanders. 3 In man, this 



1 Cameron's The Cholera Microbe and How to meet it 

 (Bailliere & Co.). 



2 Klein's Bacteria in Asiatic Cholera ; Brunton's Disorders 

 of Digestion (1888), p. 262; Thome's 'Sea-Borne Cholera' in 

 British Medical Journal, 1887 ; Straus, Roux, Nocard, and 

 Thuillier in Comptes Rendus de la Sotiete de Biologie, 1883 ; and 

 Bellews's History of Cholera in India (1885). 



Griffiths' Researches on Micro-Organisms, p. 15. 



