316 A MANUAL OF BACTERIOLOGY 



has the constitutional formula of propylglycocya- 



mine HN = C It is poisonous 



X N(C 3 H 7 ).CH 2 .C0 2 H. 



and when administered to a cat it produced 

 nervous excitement, cessation of the salivary flow, 

 convulsions, and death. This base is not found in 

 normal urines, it is therefore produced within the 

 system during the course of the disease, which is 

 highly infectious. 



Neurine (C 5 H 13 NO). This ptomaine is a constant 

 product of cadaveric putrefaction. It is a syrupy 

 base, soluble in water, and has a strong alkaline 

 reaction. It forms a crystallisable platinochloride, 

 besides other double salts. It is a poisonous base : 

 O'Ol gram, of neurine kills a cat, and 0*04 gram. 

 kills a rabbit. Brieger states that this ptomaine has 

 the same formula as trimethylvinylammonium 

 hydroxide (CH 3 ) 3 (C 2 H 3 )N.OH. 



Choline (C 5 H 15 N0 2 ). Like neurine, this ptomaine 

 is a constant product of cadaveric putrefaction. It 

 is a syrupy base, soluble in alcohol and ether, and 

 has a strong alkaline reaction. It forms double salts 

 with the chlorides of hydrogen, gold, and platinum ; 

 and it also forms compounds with carbonic and 

 sulphuric acids. When heated, choline is decom- 

 posed into glycol and trimethylamine. Choline in 

 small doses produces pyrexia: in larger doses it 

 produces paralysis due to poisoning of the motor 

 end-plates. This ptomaine has the same constitu- 

 tional formula as trimethyloxyethyleneainmonium 

 hydroxide (CH 3 ) 3 (C 2 H 4 OH)N.OH. 



