THE PROTEIN SUBSTANCES. 27 



by the sufficiently energetic action of trypsin is one peptone at last 

 obtained, the so-called antipeptone. 



KUHNE and his pupils, who have conducted these complete 

 investigations on the albumoses and peptones, classify the different 

 kinds of albumoses according to their different solubilities and pre- 

 cipitation powers. In the pepsin digestion of fibrin they obtained 

 the following albumoses: 1. Dysalbumose, which is insoluble in 

 water and dilute salt solutions. 2. Heteroalbumose, insoluble in 

 water but soluble in salt solution. 3. Protalbumose, soluble in salt 

 solution and water. These three albumoses are precipitated by 

 NaCl in a neutral solution, while 4, the D enter oalbumose, which is 

 soluble in salt solution or water, is precipitated (partly) on saturat- 

 ing with NaCl, but only after the addition of an acid. This pre- 

 cipitate is a combination of albumose and acid (HEETH). 



HERTH claims that the relative proportion of acid or alkaki, 

 salt, water, or albumose in a solution essentially changes the solu- 

 bility and precipitation power of the same. He also claims that 

 the occurrence of several different kinds of albumoses cannot be 

 demonstrated, because with one and the same albumose, the above 

 conditions being changed, its solubilities and precipitating powers 

 are changed. HAMBUEGER found the same to be true from his 

 investigations. 



The albumoses obtained from different albuminous bodies do not seem to 

 be identical. The globulinalbumoses of KUHNE and CHITTENDEN are called 

 globuloses, the vitellin albumoses of NEUMEISTER vitelloses, those of casein 

 caseoses (CHITTENDEN), those of myosin myosinoses (KUHNE and CHITTENDEN), 

 and so on. The different kinds of albumoses are distinguished as proto,- 

 hetero-, and deutero-aiseoses, etc. 



NEUMEISTER designates as atmidalbumose that body which is obtained by 

 the action of superheated steam on fibrin. At the same time he also obtained 

 a substance called atmidalbumin which stands between the albuminates and 

 the albumoses. 



Of the soluble albumoses NEUMEISTER designates protoalbumose 

 and heteroalbumose as primary albumoses, while the deuteroalbu- 

 mose, which is nearly related to the peptones, he calls secondary 

 albumose. As essential difference between the primary and sec- 

 ondary albumoses he suggests the following: The secondary albu- 

 moses are not precipitated by nitric acid in liquids free from salt, 

 nor by copper sulphate solution (2 parts in 100), nor by NaCl in 

 substance in a neutral liquid. Pure true peptones are not precipi 



