116 PHYSIOLOGICAL CHEMISTRY. 



destroyed much more slowly (TSCHIRJEW, FORSTER, PAKUM, WORM 

 MULLER), a polycythaemia is gradually produced. 



If blood of another kind is transfused, then under certain con- 

 ditions, according to the quantity of blood introduced, more or less 

 menacing symptoms appear. These appear, for instance, when the 

 blood-corpuscles of the receiver are dissolved easily by the serum of 

 the introduced blood, as, for example, the blood-corpuscles of rab- 

 bits on transfusion with a different kind of blood, or the reverse,, 

 when the blood-corpuscles of the transfused blood are dissolved by 

 the blood of the receiver; for instance, when the blood of a dog is 

 transfused with rabbit's or lamb's blood, or the blood of a man with 

 lamb's blood (LANDOIS). Before dissolving, the blood-corpuscles 

 may unite in tough agglomerated heaps, which clog up the smaller 

 vessels (LAKDOIS). On the other hand, the stromata of the dissolved 

 blood-corpuscles may also give rise to an extensive intravascular 

 coagulation causing death. 



The transfusion should therefore when possible be made with 

 the blood of the same kind of animal, and for the resuscitating 

 action of the blood it is immaterial whether or not it contains the 

 fibrin or the mother-substance of the same. The action of trans- 

 fused blood depends on its blood-corpuscles, and therefore defibri- 

 nated blood acts just like non-defibrinated (PANUM, LANDOIS). 



The quantity of blood in the different organs depends essentially 

 on the activity of the same. During work the exchange of mate- 

 rial in an organ is more active than when at rest, and the increased 

 exchange of material is combined with a more abundant flow of 

 blood. Although the total quantity of blood in the body remains 

 constant, the distribution of the blood in the various organs may 

 be different at different times. As a rule, the quantity of blood in 

 an organ can be an approximate measure of the more or less active 

 exchange of material going on in the same, and from this point of 

 view the distribution of the blood in the different organs and groups 

 of organs is of interest. According to RAISTKE, to whom we are 

 especially indebted for our knowledge of the relationship of the 

 activity of the organs to the quantity of blood contained therein, of 

 the total quantity of blood (in the rabbit) about comes to the 

 muscles in rest, to the heart and the large blood-vessels, J to the 

 liver, and \ to the other organs. 



