280 PATHOGENIC BACTERIA. 



from the eleventh up to the four hundred and fifty-ninth 

 day after vaccination was, among the inoculated, 17.24 

 times smaller, and the number of cases 19.27 times 

 smaller than among the not inoculated." 



Pawlowsky and others have found that the dog is sus- 

 ceptible to cholera, and have utilized the observation to 

 prepare an antitoxic serum in considerable quantities. 

 The dogs were first immunized with attenuated cultures, 

 then with more and more virulent cultures, until a serum 

 was obtained whose value was estimated at i : 130,000 

 upon experimental animals. 



Freymuth and others have endeavored to secure favor- 

 able results from the injection of blood-serum from con- 

 valescent patients into the diseased. One recovery out 

 of three cases treated is recorded not a very glittering 

 result. 



In all these preliminaries the foreshadowing of a future 

 therapeusis must be evident, but as yet nothing really 

 satisfactory has been achieved. 



