CONTENTS 15 



CHAPTER XVIII 



Paob 



Pathological Pigmentation 471 



Melanin 471 



Lipochroine 478 



Blood Pigments 481 



Icterus 488 



UrobiUn 495 



CHAPTER XIX 



The Chemistry of Tumors 497 



A. Chemistry of Tumors in General 499 



B. Chemistry of Certain Specific Tumors 516 



(1) Benign Tumors 516 



(2) Malignant Tumors 522 



Multiple Myelomas and Myelopathic "Albumosuria" 525 



CHAPTER XX 



Pathological Conditions Due to, or Associated with, Abnormalities 



IN Metabolism, Including Autointoxication 530 



Uremia . 532 



Toxemias of Pregnancy • 540 



Eclampsia 541 



Acute Yellow Atrophy of the Liver 547 



Chemical Changes of Acute Yellow Atrophy 550 



Acid Intoxication and Acetonuria 555 



Diabetic Coma 558 



Acidosis and Acetonuria in Conditions Other than Diabetes ... 563 



Alkalosis 566 



Acetonuria Without Marked Acidosis 567 



Fatigue 569 



The Poisons Produced in Superficial Bums 571 



CHAPTER XXI 



G astro-Intestinal "Autointoxication" and Related Metabolic Disturb- 

 ances 574 



I. The Constituents of the Digestive Fluids 575 



II. Products of Normal Digestion 575 



III. Products of Putrefaction and Fermentation 578 



A. Protein Putrefaction 578 



The Pressor Bases 584 



Alkaptonuria 586 



Cystine and Cystinuria 590 



B. Products of Fermentation of Carbohydrates 592 



C. Products of the Decomposition of Fats 592 



Results of Gastro-intestinal Intoxication 593 



Acute Intestinal Obstruction 596 



CHAPTER XXII 



Chemical Pathology of the Ductless Glands 597 



Diseases of the Thyroid 597 



The Functions of the Thyroid 597 



Chemistry of the Thyroid 599 



Chemistrj^ of Goiter 604 



Myxedema and Cretinism 607 



