NEMATODES 137 



and that the parasite prochices inucli vohitilo fatty acids, especially 

 butyric; both lecithin and cholesterol were absent. The dermatitis 

 produced by uncinaria larvie is ascribed by C. A. Smith^** to an alco- 

 hol-soluble substance. Watery extracts of Sclerostoma were found by 

 Grosso^* to cause but slight chemotaxis without eosinophilia. 



Filaria seem not to produce any apj)reciabl(! amount of toxic ma- 

 terial, if we may judge by the slight evidence of intoxication shown 

 by infected incUviduals. Jin exception may be made in the case of 

 the guinea-worm (Dracunculus or F. medinensis). This parasite 

 causes chiefly mechanical injury unless its bodj^ is ruptured, which 

 may happen in attempting to remove it forcibly; this accident is fol- 

 lowed by violent local inflammation or gangrene, which indicates 

 that some powerfully irritant substance is liberated from the torn 

 body of the worm.**" 



"8 .lour. Amer. Med. Assoc, 1906 (47), 1693. 



" Folia Hematol., 1912 (14), 18. 



8" Earthworms are said by Yagi (Arch, internat. pharmacodyn., 1911 (21), 

 105) to contain a hemoljrtic substance, "lumbricin," the properties of which he 

 describes. Nukada and Tenaka (Mitt. med. FakuU., Tokio, 1915 (14), 1), found 

 an antipyretic agent which seems to be derived from tyrosine. 



