xiv CONTENTS 



CHAPTER XIX. 



INFLUENZA, WHOOPING-COUGH, PLAGUE, MALTA FEVER. 



PAGE 



Influenza bacillus Microscopical characters Cultivation Dis- 

 tribution Experimental inoculation Methods .of examina- 

 tion Whooping-cough bacillus Microscopical characters 

 Pathogenic effects Methods of examination Bacillus of 

 plague Microscopical characters Cultivation Anatomical 

 changes produced and distribution of bacilli Experimental 

 inoculation Paths and mode of infection Toxins, immunity, 

 etc. Preventive inoculation Anti-plague sera Methods of 

 diagnosis Malta fever Micrococcus melitensis Relations to 

 the disease Mode of spread of the disease Methods of 

 diagnosis . . . . . . . 467 



CHAPTER XX. 



DISEASES DUE TO SPIROCH^TES THE RELAPSING FEVERS, 

 SYPHILIS, AND FRAMBCESIA. 



Relapsing fever and African tick fever Characters of the spirochsete 

 Relations to the disease Immunity African tick fever 

 Transmission of the disease Syphilis Microscopic characters 

 of spirochsete pallida Distribution Cultivation Trans- 

 mission of the disease --Serum Diagnosis Wassermann 

 reaction Frambcesia or Yaws . 494 



CHAPTER XXI. 

 IMMUNITY. 



Introductory Acquired immunity Artificial immunity 

 Varieties Active immunity Methods of production At- 

 tenuation and exaltation of virulence Passive immunity 

 Action of the serum Antitoxic serum Standardising of 

 toxins and of anti-sera Nature of antitoxic action Ehrlich's 

 theory of the constitution of toxins Antibacterial serum 

 Bactericidal and lysogenic action Hsemolytic and other 

 sera Methods of the hsemoly tic tests Opsonic action Ag- 

 glutination Precipitins Therapeutic effects of anti-sera 

 Theories as to acquired immunity Ehrlich's side-chain theory 

 Theory of phagocytosis - Natural immunity Natural 

 bactericidal powers Natural susceptibility to toxins 

 Supersensitiveness or anaphylaxis The serum disease in man 512 



