x CONTENTS 



CHAPTER III 



PRELIMINARY EXPERIMENT OF BACTERIAL CELLULAR SUBSTANCES 

 They consist essentially of complex proteins, each of which contains 

 a poisonous group 37 



CHAPTER IV 



THE CHEMISTRY OF BACTERIAL CELLULAR SUBSTANCES 

 Their protein, nuclein, carbohydrate, fatty and amino constituents 52 



CHAPTER V 



THE CLEAVAGE OF PROTEINS WITH DILUTE ALKALI IN SOLUTION 



IN ABSOLUTE ALCOHOL 



Bacterial, vegetable, and animal proteins can be split into poison- 

 ous and non-poisonous parts; the former are non-specific, the latter 

 are specific; the exact nature of neither of these portions is yet known 95 



CHAPTER VI 



ACTION OF ANIMALS 



The action of the living bacillus, of the dead bacillus, and of the 

 poisonous split product 119 



CHAPTER VII 



THE PRODUCTION OF ACTIVE IMMUNITY WITH THE SPLIT 



PRODUCTS OF THE COLON BACILLUS 



The establishment of a certain degree of tolerance with the poi- 

 sonous product; this is non-specific; the production of a mild degree 

 of immunity with the non-poisonous product; this is specific . . 137 



CHAPTER VIII 



THE SPLIT PRODUCTS OF THE TUBERCLE BACILLUS AND THEIR 



EFFECTS ON ANIMALS 



The cellular substance ; the cell poison ; the cell residue ; the precipi- 

 tate poison; the precipitate residue; the final filtrate; the action of 

 these on animals; the effects of the tuberculo-poison; sensitization 

 with tuberculo-protein; the relation of tuberculo-sensitization to 

 immunity 164 



