THE CLEAVAGE OF PROTEINS WITH ALKALI 115 



nucleic acid and the nucleates are the only nucleo com- 

 pounds in which the ratios are at all comparable with 

 those given in the preceding table. Nuclein contains a 

 little less phosphorus than any of these preparations from 

 the germ, while other nucleo compounds are much richer 

 in nitrogen and poorer in phosphorus. It is perhaps worthy 

 of mention that contact with mineral acid apparently 

 breaks up the nucleic acid, the phosphoric acid going into 

 solution; thus, preparation A gives evidence of phosphorus 

 in inorganic combination, while G does not." 



In a later paper, Leach 1 has made a study of the hapto- 

 phor of egg-white. The percentages of ash, nitrogen, phos- 

 phorus, and sulphur in egg-white and its split products 

 are given and compared with the cellular substance of the 

 colon bacillus in the following table: 



Egg-white . 

 Toxophor 

 Haptophor . 



Cell substance 

 Toxophor 

 Haptophor . 



Ash. 



2.48 



1.14 



13.57 



8.61 



2.33 



33.25 



Inorganic 

 ash. 

 2.066 



12.80 



26.08 



N. 



14.48 

 13.74 

 12.67 



P. 



0,135 

 Trace 

 0.253 



10.65 2.870 



11.15 Trace 



5.56 2.340 



N ash P ash S ash 



S. free. free. free. 



2.66 14.70 0.138 2.73 



2.19 13.90 .. 2.22 



2.79 14.53 0.290 3.20 



7.52 3.990 



1 Jour. Biol. Chem., 1908, v, 253. 



