276 PROTEIN POISONS 



TABLE XXVI 



No. Fluid. Effect. 



1 . . . . Serum (3 c.c.) Dead in four minutes 



2 .... Liver Dead in four minutes 



3 .... Kidney Dead in four minutes 



4 .... Spleen Convulsions, recovered 



It should be remarked that in all instances in which 

 symptoms followed they were characteristically those of 

 the protein poison. 



4. With the serum or extract of the same animal em- 

 ployed in Table XXVI, but with the incubation prolonged 

 to ninety minutes, the effects were less marked, as recorded 

 in Table XXVII. 



TABLE XXVII 



No. Fluid. Effect. 



1 .... Serum (3 c.c.) First and second stages 



2 .... Liver Convulsions, recovery 



3 .... Spleen Slight 



4 .... Kidney First and second stages 



We infer from this that the digestion continued until 

 the poison was in part destroyed. 



5. With the serum and extracts from the same animal 

 employed in Tables XXVI and XXVII, but the fluids after 

 the addition of the egg-white kept in the cold room for 

 twenty-four hours, the effects were not marked, as shown 

 in Table XXVIII. 



TABLE XXVIII 



No. Fluid. Effect. 



1 .... Serum None 



2 .... Liver None 



3 .... Kidney Slight scratching 



4 . . . . Spleen None 



6. With the serum and extracts obtained from an animal 

 killed seventeen days after being sensitized to egg-white, 

 the effects varied with the time of incubation, as recorded 

 in Table XXIX. 



