PROTEIN FEVER 379 



after neutralization with sodium bicarbonate. Fig. 13 

 needs no further explanation. 



The Effects of Intra-abdominal Injections of Egg-white. 

 Large single or repeated doses of egg-white injected intra- 

 abdominally in non-sensitized rabbits have but little effect 

 on the temperature. Generally the temperature runs slightly 

 subnormal after such injections. 



August 22, 1909, we injected the whites of three eggs 

 into the abdominal cavity of a rabbit. The highest tem- 

 perature of the fore period was 100.9. After the injection 

 the temperature was taken every two hours from 8 A.M. 

 to 6 P.M. up to September 6. The animal was weighed 

 each day and its urine measured and tested for albumin. 

 There was no fever; indeed, the morning temperature 

 fell some days to 97 and one day to 96.6. The animal lost 

 in weight, slightly more than one-fifth of its original weight. 

 The volume of urine averaged normal, and at no time did 

 it contain albumin. 



On the other hand, 0.05 c.c. of egg-white, filtered through 

 cotton, injected intra-abdominally every half hour from 

 8 A.M. until 4 P.M. produced the following results: 



Time. Dose in c.c. Temperature. 



8.00 A.M. 0.05 102.8 



8.30 0.05 101.0 



9.00 0.05 102.6 



.9.30 0.05 102.9 



10.00 0.05 102.6 



10.30 0.05 103.2 



11.00 0.05 103.4 



11.30 0.05 103.5 



12.00 0.05 103.4 



12.30 P.M. 0.05 104.4 



1.00 0.05 104.8 



1.30 0.05 105.1 



2.00 0.05 105.3 



2.30 0.05 105.3 



3.00 0.05 105.8 



3.30 0.05 105.8 



4.00 0.05 105.8 



4.30 106.6 



5.00 106.6 



5.30 106.1 



8.00 104.1 



8.00 A.M. 103.0 



