PROTEIN FEVER 



381 



Group /.The initial dose in this group was 1 c.c. of 

 egg-white diluted with an equal volume of physiological 

 salt solution and passed through a Berkefeld filter. Each 

 cubic centimeter of this dilution contained 26 nag. of protein. 

 The doses were increased by 1 c.c. at each repetition, which 

 was hourly. 



In rabbit No. 2 the highest temperature of the fore period 

 was 101.4. The following table shows the results: 



Time. 



8.00 



9.00 



10.00 



11.00 



12.00 



3.00 



5.00 



Dose in c.c. 

 1 

 2 

 3 

 4 

 5 

 6 

 7 

 8 

 9 

 

 



Temperature. 

 100.8 

 103.2 

 104.3 

 104.6 

 105.4 

 105.6 

 106.1 

 105.2 

 102.2 

 100.5 

 Death 



This animal died with a sudden convulsive movement. 

 The urine of the day and that in the distended bladder after 

 death was tested for albumin with negative results. Fig. 14 



XFIRST INJECTION CF SERIES 



-{-DEATH 



FIG 14. Acute fatal fever produced in a rabbit by repeated 

 intravenous injections of egg-white. 



