PROTEIN FEVER 389 



Morse has been kind enough to make a few autopsies for 

 us. We make a short abstract of his report: 



Rabbit A received intravenously four doses of 10 c.c. 

 each of a dilution of egg-white with an equal volume of 

 physiological salt solution. The doses were administered 

 at intervals of one hour. During the administration of the 

 fourth dose the animal died in convulsions. A gray rabbit 

 of average size and well-nourished; external orifices are 

 normal; mucous membranes cyanotic; body, cold; rigor 

 mortis, moderate. The peritoneal cavity contains a small 

 amount of blood-tinged, serous fluid. Superficial inspection 

 reveals nothing else of note. There is no displacement of 

 organs, no peritonitis, no area of hemorrhage in the serosa. 

 The pericardial sac is normal. There is no increase of 

 pericardial fluid and the pleural cavities are dry. In the 

 anterior mediastinum there- is a moderate amount of pale 

 fat with a few petechial hemorrhages. The thymus is 

 large, swollen, and edematous. It spreads over the anterior 

 mediastinum covering the great vessels and it contains 

 hundreds of miliary hemorrhages. There are no large 

 areas of blood in the tissue. The heart is moderately 

 dilated and filled with red clot. There is no imbibition 

 of hemoglobin in the intima of the great vessels. The 

 heart valves are normal, the myocardium is darker than 

 normal, and drips blood too freely. The lungs are reddish 

 pink, though slightly darker than normal and rather moist 

 on section. There is no pneumonia and no solid areas are 

 seen in the lung tissue. The spleen is slightly congested 

 and darker than normal. The kidneys are dark, congested, 

 and drip blood on section. The adrenals are apparently 

 normal. The stomach and intestine show no abnormality. 

 The bladder is empty and normal in appearance. The liver 

 is large, dark, and bleeds freely on section. In the retro- 

 peritoneum there is a moderately large suffusion of blood 

 through the cellular tissue and partially involving the head 

 of the pancreas. The brain appears normal, but section 

 shows the tissue somewhat congested and moist. 



The chief microscopic findings may be stated as follows: 



