426 



PROTEIN POISONS 



The increased percentage of large mononuclear leukocytes 

 is but a transitory affair, however, which usually lasts from 

 four to ten hours, and it is impossible to produce fatal 

 results in rabbits by intravenous injections of cancer-cell 



FIG. 31 



1-SO-18 1-81-12 2-1-18 



P.M. 8 A.M. 



FIG. 32 



FIGS. 31 and 32. A, rabbit 167 W., given 5 minims of 1 per cent, sar- 

 coma at 8.30, 9.30, and 10.30 A.M.; B, rabbit 54 T., given 5 minims of 1 

 per cent, sarcoma at 1, 2, and 3 P.M.; at 12.15 P.M., 10 c.c. of breast car- 

 cinoma-cell emulsion (Mel.) was injected intraperitoneally ; rabbit died 

 in eight to ten hours. 



emulsion after this stage is passed. Consequently we 

 have applied the term "transitory sensitization" to this 

 phenomenon. 



If we bleed a rabbit at the height of this transitory sensi- 

 tization and obtain the serum, this, when mixed with cancer- 



