SPECIFIC FERMENTS OF THE CANCER CELL 427 



cell emulsion and incubated for one hour will produce 

 marked symptoms of poisoning when injected intravenously 

 into a normal rabbit. The severity of symptoms depends 

 upon both the amount of cancer-cell emulsion and serum. 



FIG. 33 

 A 



1-23-12 1-24-12 1-25-12 



2.49 4.30 8.30 



4 P.M. 11 A.M. 



FIG. 34 

 B 



1-17-13 1-18-12 1-19-12 



1 P.M. 4 P.M. 8 P.M. 4 P.M. 8 A.M. 12 IK 



p 



s. 



7\ 



N 



/ 



A 



FIGS. 33 and 34. A, rabbit 54 Br., given 5 minims of 1 per cent, sarcoma 

 at 1, 2, and 3 P.M.; B, rabbit 54 Bl., given 5 minims of 1 per cent, sarcoma 

 at 1, 2, and 3 P.M. 



Given 5 c.c. of cancer-cell emulsion and 10 c.c. of the serum, 

 a rabbit of from 500 to 1000 grams will be sick but will 

 invariably recover. 



The next step was to ascertain whether the specific 

 ferment could be removed from the large mononuclear leuko- 

 cytes. For this purpose rabbits were sensitized to the 



