SMALLPOX, SYPHILIS; CANCER, ETQ 187 



of the small rounded bodies, which have already been con- 

 sidered as they arise from the flowing of cliromatin matter 

 along the spindle. In 15 is a cell containing two chromatin 

 masses. From the lower one of these a stream of chromatin 

 particles is passing into a limited area of the cytoplasm ; 

 and near the same chromatin mass are two rounded bodies. 

 Above is a second chromatin mass adjoining a round body 

 with slender peripheral rays. From long and close study 

 of the cells of this tumour I have no doubt that such round 

 bodies arise from the mixture of a chromatic and a non- 

 chromatic substance, and that they are minute amoebulae, 

 termed gemmules in Part II. Achromatic strands of linin are 

 seen in 8. Another mode of amoebula-formation is that 



the amoeboid character ; S, a similar parasite with streaming of 

 chromatin from the chromidial central part ; 6, chromatin appearing 

 as a ring of filaments around a central chromidial mass ; 7, parasite 

 with central mass of chromatin and an irregular spindle a bud 

 forming to the right ; 8, similar to 7, but with several chromatin 

 masses and peripheral formation of " gemmules " ; 9, parasite with 

 basiphile chromatin in process of formation around oxyphile masses ; 



10, same as 9 below, and a spindle with ordinary chromatin above ; 



11, parasite with chromatin in foci somewhat resembling leucocytes ; 



12, parasite similar to 9, but with basiphile chromatin in a network 

 enclosing three oxyphile bodies : such stages in the parasites simulate 

 nuclei of somatic cells ; 13, a parasite with radial moniliform chro- 

 matin ; 14, parasite with chromatin in a form resembling an irregular 

 spireme a " giant mitosis " ; 15, a parasite showing below the 

 formation of an amoebula by chromatin streaming into a localized 

 area, and elsewhere stages in amoebula-formation ; 16, a parasite with 

 multiple amoebula-formation at the surface : also a free amoebula 

 provided with tentacles, and four leucocytes ; 17, a parasite with 

 central amoebula-formation ; 18, a parasite from which gemmules 

 have been formed, and all but three have escaped ; 19, a reticulum 

 from which all the amoebulae have escaped. X 1000 From Part II 



