THE LUNG PLAGUE. 53 



Dr. Willems observed that inoculations whicli were usually accideutal 

 in man were unattended by ill effects. 



A second series of experiments was performed on cattle. The first 

 group of these was as follows: 



The second group of observations is indicated below: 



Fifteen days after the inoculation small tumors were observed at the 

 root of the tail, so as to cause this organ to be slightly raised. In one 

 the tumor speedily disappeared; in the other the swelling enlarged, 

 became very hard, attained the size of a hen's egg, was situated between 

 the anus and the root of the tail, and yielded gradually, without suppu- 

 rating, to scarifi(;ations and a saline purgative. 



Of the five other bullocks four showed no signs; the fifth, three weeks 

 after the inoculation, manifested a swelling of the head on the operated 

 side. Two incisions were made, emollients applied, and a purgative 

 administered. Low diet was also prescribed. On the 20th of April the 

 whole side of the head was swollen and almost of scirrhous hardness. 

 Two deep incisions were made without finding pus. In the nose, at tlie 

 point where the inoculation was performed, was a wound of unhealthy 

 aspect from which a sanious pus was discharged. The ox grew lean. On 

 the 17th of May a little pus flowed from the two incisions made on the 

 20th of April; afterwards much pus flowed from these incisions, as well 

 as shreds of areolar tissue and portions of dead skin. The tuinor was 

 subsiding. On the 22d of May a fluctuating tumor appeared below the 

 j aAvs, from whicli much indolent-looking jms escaped. From that moment 

 the ox began to thrive, notwithstanding that the suppurations continued 

 till the 5th of June. By the 10th of June recovery was complete. Br. 

 Willems despaired for several days of this animars return to health, and 

 he resolved not to inoculate again in the same region. 



THIRD GROUP OF OBSERVATIONS. 



On the 10th of May Dr. Willems inoculated nine Dutch bullocks and 

 two lean Belgian cows. He made two punctures in the tail of each and 



