54 DEPARTMENT OF AGRICULTURE. 



used blood expressed from the muscles and liquid squeezed out of the 

 lung of a cow .sutt'ering under the third stage of pleuropneumonia. 



Severalbullocks showed the effects of inoculation by the 10th of May ; 

 two more severely than the rest. On the 21st of IMay there was a decided 

 swelling of the tail in six bullocks and one cow. Incisions were made to 

 relieve the parts, emollients applied, and purgatives administered. 



On the 20th of May seven out of the nine bullocks and one cow pre- 

 sented considerable tumefaction at the root of the tail; incisions and 

 emollients were resorted to. On the 31st of May the swelling of the 

 parts inoculated disappeared, and the animals regained their appetite and 

 vivacity. 



Two of the nine bullocks by this time suffered much ; the root of the 

 tail, the tissues around the anus, and the nates, were consolidated and 

 enlarged by a deposit. In spite of all efforts, the free excision of the ma- 

 terial so as to produce an artificial anus, the obstacle to defecation was so 

 great, the straining so violent and constant, and the vital iiowerssunk so 

 low, that on the 8tli of June they died. Dr. Willems observed that in 

 incising these tumors the animals suffered no pain. 



On the Otli of June these animals were dissected. One presented a 

 general health of the internal organs. The lesions were localized in the 

 anal region. The muscles and other tissues around were of a pale red 

 color, interspersed by degenerated tissue. There was no suppuration. The 

 anus and its siuToundings for at least twelve inches in diameter appeared 

 gangrenous. The lungs were of dark color, slightly congested, and pre- 

 senting but the slightest trace of marbled hepatization. The gall blad- 

 der was found full of black dense bile. There was slight serous effusion 

 in the peritoneum, and the mucous lining of the intestines presented red 

 or brown punctiform discolorations and some patches of red injection. 



In the second bullock the lesions were more extensive. The mortifi- 

 cation of tissues extended up the rectum a distance of six inches. The 

 peritoueunr was inflamed, in some parts adherent by its opposing sur- 

 faces, and a reddish serositj' was effused in its cavity. The liver was 

 softened, degenerated, of a light yellowish color. The mucous membrane 

 of the tongue and windpipe was of a dark brovvni color. The lungs were 

 black, flaccid, and in the pleimil sacs was a citrine-colored serous 

 exudation. In the general disorganization of the organs of this animal 

 the most interesting feature was a number of cysts, with delicate walls, 

 distended by a dried homogeneous material similar to that inclosed in 

 the intestinal tubercles of animals that die of pleuro-pneumonia. Some 

 of these little saccules were in the folds of the peritoneum, but the major- 

 ity, at least sixty, were in the thorax and on the internal surface of the 

 ribs. 



