THE LUNG PLAGUE. 61 



perished. The operation had not the least intiiieuce upon the beasts 

 which, at the time it was performed, were evidently affected with pleuro- 

 pneumonia. Several beasts that were known for some time to have been 

 affected with pleuro-pueumonia experienced not the least effect from 

 the inoculation. 



The report from which the above has been extracted bears the date 

 of the 21st of September, 1852, and the results are indicated by the 

 annexed table. 



The second report, bearing date of the 28th of December, 1852, and 

 prepared by the same commission, furnishes facts recorded in the sub- 

 joined table. 



The conclusions drawn from the experiments were summarized as fol- 

 lows: 



1. Although the inoculation of pleuropneumonia is not, in all respects, 

 an inoffensive operation — as extensive derangements and even death 

 may result from it — its effects are generally confined to the part where 

 it has been applied. 



2. In order to prevent, as much as possible, its unfavorable conse- 

 quences, it is necessary to use some precaution, both in the selection of 

 the matter for inoculation and the period of its application. The sea- 

 son, the atmospheric circumstances, the state of nutrition, exert consid- 

 siderable influence upon the success. The autumn appears, for more 

 than one reason, to be the most suitable period. 



3. When an intense action and serious casualties appear locally and 

 in the more distant organs, they may be attributed to exterior circum- 

 stances and to the individual constitution. This being the case, casu- 

 alties cannot always be avoided. 



4. If serious complications appear and affect the essential organs so as 

 to cause the reaction of the whole organism, it is as difficult to prevent 

 them and arrest their progress as it is to cure pleuro- pneumonia. 



5. In the violent cases, terminating in death, lesions in the thorax or 

 the lungs have never been met ; hitherto they have always been concen- 

 trated in the abdominal cavity. 



6. The inoculation produces no unfavorable effects either upon the 

 constitution or the yield of milk, while its action is limited to a local 

 affection. Only in the cases where abundant deposits succeed a too 

 intense local action do the animals continue sickly during some time. 



7. The operation has not had a determined influence on the excitement 

 of cestrnm. In proportion this has been more frequent on the inocu- 

 lated than on the uninoculated cows. It is, however, to be remarked 

 that No. 25 has not yet been in heat, although the period for it has long 

 since passed. 



8. Tlie return of the uterine heats with the two cows Kos. 5 and 12, 

 prol)ably in consequence of abortion, can the less be referred to the inoc- 

 ulation, as these two cases are isolated, and the effects were not observed^ 



