THE LUNG PLAGUE. 65 



Seventy-four lost the tail up to the root. 



Three hundred and four lost it in part. 



Seventy-three contracted exudative pleuro -pneumonia after having 

 been successfully inoculated. 



After careful examination it resulted at fifty-five cases of exudative 

 pleuro-pneumonia, well attested, occurred upon beasts inoculated with 

 unequivocal success. The space of time which elai)sed with these ani- 

 mals between the inoculation and the first appearance of the pneumonia 

 symptoms, varies 17 to 136 days. 



After an elaborate analysis of cases in which the inoculation seems to 

 have been effectual, of others in which the operation and immunity 

 seemed to be coincidences, and lastly of those in which it was not pre- 

 servative, the commission concludes : 



1. That tlie iuoculatioii witli tlie liquid extracted from a lung liepatized in consequence 

 of exudative pleuro-pneumouia, is not an absolute preservative against that disease. 



2. That the phenomena succeeding the inoculation may occur several times niion the 

 same animal, whether it has or has not been affected with exudative pleuro-pneumouia, 

 and that the two affections -may go on simultaneously in one and the same indivi<lual; 

 considerable derangements ajjpear at the inoculated jjart, while the morbid action of 

 the lungs progresses towards a fatal termination. 



As to the point whether inoculation really possesses a jtreservative virtue, and in 

 that case, in what proijortion and for what duration it maintains the immunity in the 

 animals that have undergone it, this question can only be resolved by ulterior researches. 



A summary of inoculations performed and results obtained is appended 

 in a tabular form at the close of the report. 



We now come to the experiments of the French commission, and it 

 must not be forgotten that, in connection with the subject of the trans- 

 mission of the lung plague by contact, this commission had resorted to 

 inoculation independently of any suggestions on the part of Dr. Willems. 



The general resume, ably set forth by Professor Bouley, is regarded 

 uj) to the present day as having done much to diffuse a rational belief in 

 the efficacy of inoculation, and the experiments were conducted with 

 great care and skill. 



Experiments were instituted by the commission — 



First. To ascertain whether i)leuro-pneumonia is susceptible of being- 

 transmitted to healthv animals bv the inoculation of blood, saliva, nasal 

 discharge, and excrementitial matters from animals affected with the 

 disea.se. 



Second. Have animals thus inoculated enjoyed any immunity against 

 the contagious inlim^ice of the lung plague? 



Third. Is pleuroi)neumonia capable of being transmitted, in all its 

 forms and characteristic symptoms, to healthy cattle by the inoculation 

 of the liquid extracted from the lungs of a sick animal? 



Fourth. In the case where inoculation of this liquid does not determine 

 on healthy animals an exact repetition of the form and symi)toms of the 

 original disease, what are the local or general ])henomena which result*? 

 In what proportion and to what extent do these characters, more or h'ss 

 severe, transmit themselves ? How many aninuils die after inoculation? 

 5 



