REACTION OF CELLS 



67 



The agglutinins in their action on bacteria seem 

 to behave very nearly in the same manner as the 

 haemolysins in regard to red blood-corpuscles. The 

 following figures of MADSEN, who observed the time 

 t which was necessary for producing a given degree 

 of agglutination of Bacillus coli at 37 C. when a 

 given quantity q of coli-agglutinin acted upon this 

 bacillus, show that the ^-rule is very nearly obeyed. 



AGGLUTINATING ACTION OF DIFFERENT QUANTITIES OF 

 COLI-AGGLUTININ AT 37 C. 



The value of qt decreases a little with decreasing 

 quantity. But on the whole the ^/-rule holds pretty 

 well. 



The dependence of the action of this agglutinin 

 on temperature is shown by the following table. It 

 gives the quantity, ^ obs ., of agglutinin, necessary for 

 producing a given degree of agglutination in 10 

 minutes at the temperature written in the first 

 column. The calculated values, ^ calc ., are found by 

 means of the formula on p. 49. 



