DIGESTION AND RESORPTION 83 



KHIGINE. The "small stomach" of the dog used 

 by LONNOUIST secreted about 4 per cent of the total 

 secretion. 



Professor LONDON and Dr. LONNQUIST have 

 investigated the content of gastric juice in the 

 stomach after a meal or after introduction of food 

 through a tube. In the first case the content is 

 nearly constant during four hours, and subsequently, 

 when digestion is nearly completed, sinks rapidly. 

 In the second case the content of juice and pepsin is 

 at first very small, but increases rapidly afterwards. 

 For the calculations I have made the simplified 

 hypothesis that the concentration of pepsin is pro- 

 portional to the time of digestion, which agrees 

 fairly well with the experiments of KHIGINE and 



LOBASOFF. 



After these preliminary remarks we will consider 

 the interesting results of KHIGINE'S experiments 

 given in the table below. Different quantities of 

 the commonest food -stuffs (recorded in the first 

 column) were given the dog to eat, or introduced 

 into the stomach by means of a tube. It is very 

 obvious that the total quantity of gastric juice 

 (tabulated in the third column) is proportional to the 

 quantity of food (tabulated in the second column), if 

 this is of the same kind. KHIGINE has also drawn 

 this conclusion, according to which the calculated 

 values in the fourth column are evaluated. The 

 good agreement between these figures and the 

 corresponding observed values gives a proof of the 

 said proportionality. 



