112 



CHEMICAL EQUILIBRIA 



was carried out in February 1902, the second (toxicity 

 T n ) 19 months later, i.e. in September 1903. As is 

 seen, they agree very closely with each other, so that 



NEUTRALIZATION OF ONE EQUIVALENT OF DIPHTHERIA POISON 

 BY n EQUIVALENTS OF ANTIDIPHTHERIC SERUM 



K = 0-0093 



the discrepancy between them is without doubt due 

 to experimental errors. After the observed values 

 T! and T n are given values calculated according to 

 the law of GULDBERG and WAAGE, if two molecules 

 of the compound are formed from one molecule of 

 the poison and one molecule of the antitoxin. The 

 formula is : 



(Cone, of free toxin) (Cone, of free antitoxin) = K (Cone, of neutralized toxin) 2 . 



As is seen, they agree perfectly with the observed 

 figures within the errors of observation, which may 

 be estimated from the differences between the two 



