IMMUNIZATION 



157 



AGGLUTININ IN THE BLOOD OF A PATIENT IN TYPHOID 

 FEVER (JORGENSEN) 



Till the twentieth day the decrease of the content 

 of agglutinin in the patient's blood goes on quite 

 regularly, so that it sinks to its half-value in 8-4 

 days. But in the last 15 days the quantity of 

 agglutinin is rather greater than the calculation 

 indicates. Perhaps this circumstance is partly due 

 to errors of observation, but the regularity of the 

 figures seems to indicate that the decrease goes on 

 much more slowly than in the former part of the 

 process. In a similar manner it has often been 

 found with strongly immunized animals that they 

 retain the last traces of immunity for a long time 

 undiminished or falling off very slowly. It seems 

 as if a part of the antibodies were stored up in parts 

 of the body, from which it very slowly diffused back 

 to the veins. Still more pronounced is the second 

 instance. 



