PATHOLOGICAL VARIETIES OF LEUCOCYTES 33 



evidently does not belong to that variety. The domestic fowl has 

 an eosinophile leucocyte with round granules, similar to the 

 eosinophile found in mammalian blood. As stated above the 

 nucleus of the avian polymorph varies much exhibiting the same 

 shapes as in mammals. In affinity for stains the granules resemble 

 the polymorphs rather than the eosinophiles. The cells have ac- 

 tive ameboid movement. In its physiologic properties, this cell 

 resembles the polymorphonuclears. This is the cell found in 

 abundance in purulent exudates and is the one that reacts in acute 

 inflammatory conditions as does the mammalian polymorphonu- 

 clear. 



Variety IV. Eosinophiles (coarsely granular oxyphile cells). 

 The nucleus is poh'morphous, ordinarily being bi- or tri-lobed. 

 The lobes are coarsely reticular and usually stain well. The cell 

 body contains many coarse, strongly acidophile granules which 

 are commonly round in outline though oval, ovate or oblong ones 

 are found. In the cat these granules are ordinarily short rod- 

 shaped with rounded ends. The granules vary in size in the dif- 

 ferent species. In the horse they are very large, generally one to 

 one and one-half micra in diameter. These cells are of about the 

 size of the polymorphonuclears. 



Variety V. Mast cells (coarsely granular basophile cells, 

 Kanthack and Hardy). In this variety the nucleus usually takes 

 the stain so faintly that it is difficult to make out its shape. It 

 varies in shape from rounded or curved to bi-, tri- or many Iobed. 

 The cell body contains many strongly basophile rounded or oval 

 granules that take a deep violet tint with Jenner's and a royal 

 purple with Wright's stains. Mast cells are as a rule slightly larger 

 than eosinophiles. 



PATHOLOGICAL VARIETIES OF LEUCOCYTES 



Besides the varieties just described which are found in normal 

 circulating blood there are other kinds that are sometimes found 

 in pathological conditions. In some cases of disease severe enough 



leucocyte is homologous with the mammalian polymorphonuclear was first 

 stated in a paper read before the American Association of Pathologists and 

 Bacteriologists on May 7th, 1907. It was first published in the first edition 

 of this book, March, 1908. 



