08 VARIATIONS IN NUMBER OF RED CORPUSCLES 



size may be observed. There may be several very small corpuscles 

 (microcytes) and corpuscles larger than normal (megalocytes). 

 In very young animals a much greater variation in size than occurs 

 in adults is normal. Some of the corpuscles may show irregularity 

 in staining, showing either as a diffuse basophile staining (poly- 

 chromasia) or as separate bluish points within the corpuscles 

 (punctate basophilia). Corpuscles with deformed shapes may be 

 found (poikilocytosis), a commonly occurring form being pear- 

 shaped with a pointed projection at one end. These several 

 changes may be present in slight or in marked degree. Besides 

 the changes mentioned nucleated red cells may be found in the 

 circulating blood. Normoblasts with a compact deeply stained 

 nucleus situated usually in one side of the cell are the forms or- 

 dinarily observed. Megaloblasts usually with large, rather pale 

 nucleus sometimes showing irregular karyokinetic figures are 

 sometimes observed. Microblasts may occur, but are rare. 



Table XXI. — The Following Cases Illustrate Different Grades of 



Anemia 



REFERENCES 



1. Ahmand-Delille et Mayer. Experiences sur l'hyperglobulie des 

 altitudes. Journ. d. Physiol, et Path, gen., vi, 1904, p. 466. 



2. Burnett, S. H. A study of the blood of normal guinea pigs. Journ. of 

 Med. Research, xi, 1904, p. 537. 



