EXPERIMENTAL LEUCOCYTOSIS 



75 



a bad sign as showing lack of resistance on the part of the patient. 

 The increase of leucocytes occurs more rapidly in cases where the 

 course of the disease is more favorable. Ordinarily leucocytosis 

 is established within one-half to two hours after the initial decrease. 

 Inflammatory leucocytosis has been observed in strangles, in- 

 fection with pyogenic organisms, fistulous withers, wound infec- 

 tions, abscesses, quittor, suppurations, pneumonia (croupous, 

 pleuro, gangrenous and broncho), pleuritis, muscular rheumatism, 

 tetanus. In man it occurs in a large number of diseases some of 

 which are: Asiatic cholera, relapsing fever, typhus fever, scarlet 

 fever, diphtheria, tertiary syphilis, erysipelas, bubonic plague, 

 dysentery, pneumonia, smallpox (suppurative stage) and vaccina, 

 malignant endocarditis, multiple abscesses, pyemic and septicemic 



Table XXII. — Examples of Inflammatory Leucocytosis 



* The letters following the animal refer to the investigator reporting the 

 case; — B for Buffington, M for Meier, M H C for Moore, Haring and Cady. 



conditions, actinomycosis, glanders, acute articular rheumatism, 

 gonorrhoea, cerebro-spinal meningitis, osteomyelitis, whooping 

 cough, abscesses, inflammation of serous membranes, gangrenous 

 inflammation. 



Experimental leucocytosis. Besides natural infections, leu- 

 cocytosis may be induced by many influences. A large number 

 of chemical substances and mixtures, organic principles, bacterial 



