80 INFLUENCES AFFECTING THE LEUCOCYTES 



in a day. With rapid or sudden death the ante-mortem increase 

 does not occur. Ordinarily the increase is in the polymorphs; 

 sometimes it is mainly in the lymphocytes. Small numbers of 

 myelocytes and erythroblasts have been found in the circulating 

 blood. 



The leucocytosis is believed to be due in the majority of cases 

 to terminal inflammation or stasis. V. Limbeck considered that 

 the cause, as a rule, is an inflammation of the respiratory passages, 

 since he was always able to find such a cause, e. g., patches of 

 pneumonia or broncho-pneumonia, septic bronchitis, or hypostatic 

 pneumonia. 



LYMPHOCYTOSIS 



In the young the lymphocytes are generally present in greater 

 numbers than in adults. In puppies 3-20 days old, there were 

 20.8-30.7% while the average for adults is 19.4%. A lymphocy- 

 tosis is constantly present (Goodall, Gulland and Paton) during 

 digestion. There are several pathological conditions in which 

 there is a relative or absolute increase of the lymphoc3'tes. In 

 anemia (secondary or pernicious), most splenic tumors, some 

 cases of lymphoma, and in infectious diseases associated with 

 acute hyperplasia of the lymphatic tissue, there is a relative or 

 absolute lymphocytosis. An increase of lymphocytes has been 

 found after injections of thyroid extract, tuberculin, pilocarpin, 

 quinine hydrochlorate, extract of carcinomatous tissue, and after 

 splenectomy. A relative lymphocytosis due to the decrease of the 

 polymorphonuclears is found during the early (leucopenic) stage 

 of inflammatory leucocytosis. The most marked lymphocytosis 

 occurs in lymphatic leukemia in which nearly all the leucocytes 

 are lymphocytes. In man, lymphocytosis is found in cases of 

 whooping cough, congenital and acquired secondary syphilis, 

 typhoid fever, malaria, some cases of scurvy and hemophilia, and 

 v. Jaksch's anemia. 



EOSINOPHILIA 



A slight increase of eosinophils has been observed in man after 

 coitus. In a cow in the early stage of oestrum, Knight found 

 9,444 leucocytes of which 18% were eosinophiles. The normal 

 number of leucocytes for this cow was 5,000 of which 17.3% were 



