110 



SPECIFIC INFECTIOUS DISEASES 



in chronic cases in two horses and a guinea pig. In acute glanders 

 in man a polynuclear leucocy tosis has been observed : Cabot found 

 11,000-13,000 leucocytes of which 80% were polymorphs, Coleman 

 and Ewing found 13,000 and Wherry found 21,000-23,400. 



Mallein was observed by Bidault to produce a leucocytosis 

 which is preceded by a moderate leucopenia. The leucocytosis 

 was essentially polynuclear though in non-glandered horses the 

 mononuclears also were increased. In glandered horses, the poly- 

 nuclear leucocytosis was much more pronounced. Burnett and 

 Pearce and Mielke found the leucocytes increased in glandered 

 horses following the administration of mallein. The polymorphs 

 were uniformly affected, the other varieties sometimes increased 

 and sometimes decreased. 



Table XXXI- 



-summary of examinations of the blood of glandered 

 Horses (Burnett and Pearce). 



^ 



