MAL DE CADERAS 



139 



center of newly formed plaques. If the plaques are old (24 hrs.) 

 there may be no parasites visible; the further removed from the 

 center the puncture is made the 

 fewer are the parasites likely to 

 be (Baldrey). Before the forma- 

 tion of plaques diagnosis is diffi- 

 cult. The parasite may often be 

 found by making a microscopical 

 examination of scrapings of the 

 urethra in males or the vulva in 

 females (Baldrey). The parasites 

 are present in the blood in small 

 numbers. Ordinarily they are 

 found only by inoculating a sus- 

 ceptible animal. They are pres- 

 ent in the exudate of the male 



urethra and of the vagina, in the f ig . ig. Trypanosoma equiperdum, 

 seminal fluid and in the fluid of blood, horse (Rouget). 



edematous swellings. 



Changes in the blood. — Detailed examinations of the blood 

 have apparently not been made. From the time of the appearance 

 of the plaques there is a progressive anemia which seems to be 

 more rapid from the time of the appearance of nervous symptoms. 

 There is an increase in the number of leucocytes. Pease states 

 that there is a large increase in the number of eosinophiles. 



MAL DE CADERAS 



Trypanosoma equinum is similar in form and size to the other 

 pathogenic trypanosomes, but is readily distinguished morpho- 

 logically by the apparent absence of a centrosome, which is so 

 inconspicuous that its existence has been denied by some. In 

 Tr. equinum the centrosome measures about one-fourth to one- 

 third [X. 



The number of trypanosomes in the peripheral blood varies a 

 good deal in cases of natural infection. Sivori and Lecler state 

 that in cases of progressive anemia they are nearly always found 

 and are numerous, while in cases of parexia they are found from 

 time to time in small numbers, and in cases of paraplegia they are 



