144 INFECTIOUS DISEASES DUE TO PROTOZOA 



Theiler's experimental cases the red corpuscles fell from 6,780,000 

 to 3,000,000 per cmm. Poikilocytosis was observed. In more 

 severe cases the number may be reduced still lower, with marked 

 pathological changes in the red corpuscles, the presence of numer- 

 ous corpuscles showing punctate basophilia, many erythroblasts 

 (normoblasts and megaloblasts), microcytes and megalocytes. 

 In cases of light infection the number of leucocytes is scarcely 

 increased; but when the trypanosomes are frequent, the leucocytes 

 seem to increase in direct proportion. The eosinophiles are usually 

 increased in number and are sometimes very numerous (Theiler). 



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