^l(j Marshall and Jolly 



When the last-mentioned animal was killed two and a half months sub- 

 sequently, it was found that the graft, as far as was observed, had been 

 absorbed, only a certain amount of scar tissue being left in its place. The 

 rat's own ovaries had not been removed. 



(4) This experiment was identical with the preceding one, the result 

 being merely a persistence of scar tissue. 



(5) The ovaries were removed from a young rat and grafted together 

 into the right kidney of another rat belonging to a different litter. The 

 latter animal's own ovaries were not removed. Two and a half months 

 later it was killed, when it was found that the grafts had been absorbed, 

 their position being occupied by connective tissue. 



(6) This experiment was similar, but the grafted ovary was found to be 

 entirely degenerated after a little more than one month. 



(7) In this experiment the ovaries of a young rat were grafted into 

 the right kidnej^ of a male. On the latter being killed it was found that 

 the graft was degenerated and palpably in process of absorption. 



(8) The ovaries were removed from a young rat and grafted into 

 the right kidney of another female belonging to the same litter. About one 

 and a half months afterwards this rat was killed, when it was found that 

 the graft had taken perfectly, the ovaries containing normal follicles in 

 various stages of development and at least two recently formed corpora 

 lutea. Sections showed also that the ovarian tissue was in almost complete 

 continuity with the kidney tissue in which it was embedded (see figure). 

 The animal's own ovaries had not been removed. 



(9) This experiment was similar to the last, the ovaries being grafted 

 into the right kidney in a whole sister. After three months the rat with 

 the transplanted ovaries was killed, the organs being found in situ in a 

 state of partial preservation. 



(10) An ovary from one female rat was grafted into the right kidney 

 of another belonging to the same litter. The rat with the graft was killed 

 three months afterwards. Microscopic sections through the kidney revealed 

 ovarian tissue and follicles with ova in the periphery, but the central 

 part was less well preserved. The animal's own ovaries had not been 

 removed. 



(11) The ovaries were removed from a white rat. About two months 

 afterwards the ovaries were removed from a piebald rat, and one of them 

 was grafted into the left kidney of the white rat previously castrated. 

 After another six months (or eight months after the first operation) the 

 white rat was killed, when it was found that the transplantation had been 

 perfectly effected. Normal ovarian tissue in abundance, and containing 

 numerous ova, was observed in sections through the kidney. The uterus 

 showed little or no indication of degeneration. It was evident, therefore, 

 that whatever degeneration this organ may have undergone during the first 

 two months after the removal of the animal's original ovaries was arrested 

 by the successful ovarian graft, the uterus being restored (or almost restored) 



