The Effects of Thyroidectomy upon the Mammalian Pituitary 285 



LITERATURE REFERRED TO. 



(1) BoYCB and Beadles, "Enlargement of the Hypophysis Cerebri in Myxce- 

 dema, with remarks upon the Mainmahan Pituitary," Journ, of Pathol, and Bacteriol., 

 vol. i., p. 223, 1893. 



(2) Gley, -'Recherches sur la f(jnction de la glande thyroide," Arch. de. 

 physiol. normale et path., p. 311, 1892. 



(3) Herring, "The Histological Appearances of the Mammalian Pituitary 

 Body," Quarterly Journ. of Exper. Physiol., vol. i., No. 2, p. 151, 1908. 



(4) HoFMEiSTER, " Zur Physiologie der Schilddriise," Fortschritte der Medicin, 

 S. 81, 1892. 



(5) Klebs, Allgemeine Pathologie, Th. ii., S. 433, 1889. 



(6) PiSENTi and Viola, " Beitrag zur normalen und pathologischen Histologic 

 der Hypophysis und beziiglich der Verhaltnisse zwischen Hirnanhang und Schild- 

 driise," Centralbl. fur die med. Wissensch., S. 450, 1890. 



(7) RoGOWiTSCH, " Die Veranderungen der Hypophyse nach Entfernung der 

 Schilddriise," Ziegler's Beitrage zur patholog. Anat., Bd. iv., S. 453, 1889. 



(8) ScHONEMANN, " Hypophysis und Thyreoidea," Virchow's Archiv, Bd. cxxix., 

 S. 310, 1892. 



(9) Stieda, H., " Ueher das Verhalten der Hypophyse des Kaninchens nach 

 Entfernung der Schilddriise," Ziegler's Beitrage zur patholog. Anat., Bd. vii., 

 S. 537, 1890. 



DESCRIPTION OF PLATES. 



Plate I. 



Fig. 1. Median sagittal section through part of posterior lobe of the pituitary of 

 a rabbit three months after removal of both thyroids. (Photograph, x 300.) Granu- 

 lar and colloid bodies are seen in the nervous portion of the lobe ; some of the cells 

 of the pars intermedia appear on the left-hand side. 



Fig. 2. Median sagittal section through infundibular recess and neck of the 

 posterior lobe of a rabbit three months after removal of both thyroids. (Photograph, 

 X 200.) Granular and colloid bodies in neck of the posterior lobe. Some of these are 

 definite cells which pass into the infundibular recess. Budding of ependyma cells is 

 seen on the inner surface of anterior lamina on the left-hand side of the photograph. 



Plate II. 



Fig. 3. Median sagittal section through lower part of the neck of the posterior 

 lobe of the pituitary of a dog nineteen days after thyroidectomy. (Photograph, 

 X 160.) Cells of the pars intermedia seen below are invading the nervous tissue of 

 the neck of the posterior lobe. Colloid liodies are streaming inwards and accumu- 

 lating beneath the ependyma cells lining the infundibular recess. 



Fig. 4. Median sagittal section through part of the nervous substance of the 

 upper part of the neck of the posterior lobe of the pituitary of the same dog. 

 (Photograph, x 300.) The active budding of the ependyma cells, and the escape of 

 their products into the infundibular recess of the third ventricle, are shown. 



