TABLE OF CONTENTS. 



GENERAL PART. 



PAGES 



Introduction: Definition of a " Toxine," Chemically, Physio- 

 logically, and Theoretically Side-Chain Theory Mode of 

 Formation Nutrient Media Means of Promoting the For- 

 mation of Toxines Filtration Purification Chemical 

 Nature Influence of External Factors (Oxidising Agents, 

 Poisons) Fate in the Organism Formation of Antitoxine 

 Immunity Fate in the Digestive Tract Mode of Action of 

 Toxines, Specific Nature, Incubation Period Constitution 

 of Toxines Physiological Action Toxoids and Toxones 

 General Characteristics of Antitoxines, ..... 1-29 



Behaviour of Toxines towards Antitoxines : Haptophore 



and Toxophore Groups Specific Combination Units of 

 Measurement Toxoid Formation L and L + The Value 

 "D" as a Measure of Toxones Incomplete Saturation The 

 Value "200" Poison "Spectra" Physico-Chemical Meas- 

 urements Speed of Reaction Conditions of Equilibria 

 Heat Manifestation of the Action of Toxine upon Antitoxine, 29-62 



Endotoxines and Bacterial Proteins, 62-68 



SPECIAL PART. 

 I. THE TRUE TOXINES. 



Diphtheria Toxine: Secretion Nutrient Media Admission 

 of Air Preservation Purification Properties Effects 

 Toxoids and Toxones, 69-91 



Diphtheria Antitoxine: Production Preservation of Serum 

 Concentration of the Antitoxine Chemical Nature 

 Combination with Proteids of the Serum, .... 91-102 



Tetanus Toxine : Nutrient Media Properties Concentration 

 Action Relation to Central Nervous System Fermenta- 

 tion Theory Tetanus antitoxine, 102-125 



Botulism Toxine Pyocyaneus Toxine Toxine of 

 Symptomatic Anthrax, 



Bacterial HsemolysineS : Tetanolysine Pyocyanolysine 

 Colily sine Staphylolysine - Other Lysines The Leucocidine 

 of the Staphylococci, 133-144 



